# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "multiDEGGs" in publications use:' type: software license: GPL-3.0-only title: 'multiDEGGs: Multi-Omic Differentially Expressed Gene-Gene Pairs' version: 1.2.1.9000 doi: 10.34133/csbj.0001 identifiers: - type: doi value: 10.32614/CRAN.package.multiDEGGs - type: url value: https://elisabettasciacca.github.io/multiDEGGs/ abstract: Performs multi-omic differential network analysis by revealing differential interactions between molecular entities (genes, proteins, transcription factors, or other biomolecules) across the omic datasets provided. For each omic dataset, a differential network is constructed where links represent statistically significant differential interactions between entities. These networks are then integrated into a comprehensive visualization using distinct colors to distinguish interactions from different omic layers. This unified display allows interactive exploration of cross-omic patterns, such as differential interactions present at both transcript and protein levels. For each link, users can access differential statistical significance metrics (p values or adjusted p values, calculated via robust or traditional linear regression with interaction term) and differential regression plots. The methods implemented in this package are described in Sciacca et al. (2023) . authors: - family-names: Sciacca given-names: Elisabetta email: e.sciacca@qmul.ac.uk orcid: https://orcid.org/0000-0001-7525-1558 preferred-citation: type: article title: 'multiDEGGs: Single or Multiomic Differential Network Analysis for Biomarker Discovery and Feature Engineering for Predictive Modeling' authors: - family-names: Sciacca given-names: Elisabetta email: e.sciacca@qmul.ac.uk orcid: https://orcid.org/0000-0001-7525-1558 - family-names: Wang given-names: Susan S. - family-names: Pitzalis given-names: Costantino - family-names: Lewis given-names: Myles J. journal: Computational and Structural Biotechnology Journal year: '2026' volume: '35' issue: '1' doi: 10.34133/csbj.0001 start: '0001' repository: https://elisabettasciacca.r-universe.dev repository-code: https://github.com/elisabettasciacca/multiDEGGs commit: 722313aa5519aead78268a7b646788db2fcfacea url: https://github.com/elisabettasciacca/multiDEGGs/ date-released: '2026-04-17' contact: - family-names: Sciacca given-names: Elisabetta email: e.sciacca@qmul.ac.uk orcid: https://orcid.org/0000-0001-7525-1558